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November
9, 2001. Super-fast search of
query sequence over human genome (FMAP program).
It takes FMAP less than a second to map a sequence on genome. Go
to our human
genome mapping page to try the program on human genome draft.
Alternatively, you can map a sequence in Softberry
Genome Explorer and immediately see a lot of information about
mapped site - known and predicted genes, ESTs, predicted promoters
and other.
October
4, 2001. Softberry
Genome Explorer was enabled to provide visualization of
expression data in the context of annotated human genome.
As an
example, we maped a major part of Unigen sequences used in
analysis of hereditary breast cancers and presented
data from Hedenfalk et al. (New England Journal of Medicine,
v 344, n 8, p.539-548). In default window of Genome Explorer, you
can see a fragment of human chromosome 1 with two genes, first of
which is overexpressed in patients with BRCA1 mutation, while the
second - in patients with BRCA2 mutations. These data are shown as
an example of how combining proprietary expression information
with known genomic information can dramatically speed up drug
target identification (to see expression data, go to graphical
presentation of October, 2000 release of human genome, point
mouse to one of mapped brca genes, right click and select Show
Expression).
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InfoGene program takes information from GeneBank or EMBL databases and combines separate entries related to the same gene into a single entry for each gene, creating a new, gene-centered database.
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Comparison of genomic sequences:
FMAP
- map Human genome Scan to map your sequence to Human genome draft
(Click this link)
SCAN2 - program for aligning two multimegabyte-size sequences,
and
DBSCAN - database homology search program similar to BLAST, but
handling multimegabyte-size sequences.
Also: BLAST search of your protein sequence through Human or
Drosophila proteins predicted by Softberry from genome sequences
using FGENES and FGENESH programs and their derivatives.
Your
use of Softberry programs signifies that you accept Terms
of Use
Splice
sites, Protein coding exons and Gene model construction, Promoter
and polyA regions recognition
Your
use of Softberry programs signifies that you accept Terms
of Use
NEW!
You can now view all human genes - both known and predicted by our
newest FGENESH++
gene finder, - and also more than 20,000 human promoters predicted
by our TSSW program, in Softberry Genome Explorer. October,
2000 release of human genome draft is shown with known and
predicted genes, while December,
2000 release is shown with both genes and promoters.
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